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The role of neoantigens in response to immune checkpoint blockade

Immune checkpoint blockade has demonstrated substantial promise for the treatment of several advanced malignancies. These agents activate the immune system to attack tumor cells. For example, agents targeting CTLA4 and programmed cell death 1 (PD-1) have resulted in impressive response rates and, in...

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Detalles Bibliográficos
Publicado en:Int Immunol
Main Authors: Riaz, Nadeem, Morris, Luc, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Chan, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986233/
https://ncbi.nlm.nih.gov/pubmed/27048318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw019
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