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The role of neoantigens in response to immune checkpoint blockade

Immune checkpoint blockade has demonstrated substantial promise for the treatment of several advanced malignancies. These agents activate the immune system to attack tumor cells. For example, agents targeting CTLA4 and programmed cell death 1 (PD-1) have resulted in impressive response rates and, in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int Immunol
Hauptverfasser: Riaz, Nadeem, Morris, Luc, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Chan, Timothy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986233/
https://ncbi.nlm.nih.gov/pubmed/27048318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw019
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