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The role of neoantigens in response to immune checkpoint blockade

Immune checkpoint blockade has demonstrated substantial promise for the treatment of several advanced malignancies. These agents activate the immune system to attack tumor cells. For example, agents targeting CTLA4 and programmed cell death 1 (PD-1) have resulted in impressive response rates and, in...

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Dades bibliogràfiques
Publicat a:Int Immunol
Autors principals: Riaz, Nadeem, Morris, Luc, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Chan, Timothy A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986233/
https://ncbi.nlm.nih.gov/pubmed/27048318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw019
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