The immune microenvironment and neoantigen landscape of aggressive salivary gland carcinomas differ by subtype

PURPOSE: Salivary gland carcinomas (SGCs) are rare, aggressive cancers with high rates of recurrence and distant metastasis. These factors, and a lack of active systemic therapies, contribute to poor clinical outcome. Response rates with immune checkpoint blockade have been low, although clinical da...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Linxweiler, Maximilian, Kuo, Fengshen, Katabi, Nora, Lee, Mark, Nadeem, Zaineb, Dalin, Martin G., Makarov, Vladimir, Chowell, Diego, Dogan, Snjezana, Ganly, Ian, Hakimi, A. Ari, Wong, Richard J., Riaz, Nadeem, Ho, Alan L., Chan, Timothy A., Morris, Luc G.T.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918996/
https://ncbi.nlm.nih.gov/pubmed/32060100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3758
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