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A neoantigen fitness model predicts tumor response to checkpoint blockade immunotherapy
Checkpoint blockade immunotherapies enable the host immune system to recognize and destroy tumor cells(1). Their clinical activity has been correlated with activated T-cell recognition of neoantigens, which are tumor-specific, mutated peptides presented on the surface of cancer cells(2,3). Here, we...
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| 發表在: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137806/ https://ncbi.nlm.nih.gov/pubmed/29132144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24473 |
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