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Cancer Immunotherapy Using Checkpoint Blockade

The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses in patients with a variety of cancers. This can be achieved by antibodies blocking the cytotoxic T lymphocyte antigen-4 (CTL...

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Bibliographic Details
Published in:Science
Main Authors: Ribas, Antoni, Wolchok, Jedd D.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391259/
https://ncbi.nlm.nih.gov/pubmed/29567705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar4060
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