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Emerging concepts for immune checkpoint blockade-based combination therapies

Checkpoint blockade has formally demonstrated that reactivating anti-tumor immune responses can regress tumors. However, this only occurs in a fraction of patients. Incorporating these therapies in more powerful combinations is thus a logical next step. Here, we review functional roles of immune che...

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Bibliographic Details
Published in:Cancer Cell
Main Authors: Zappasodi, Roberta, Merghoub, Taha, Wolchok, Jedd D.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896787/
https://ncbi.nlm.nih.gov/pubmed/29634946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.005
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