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The role of neoantigens in response to immune checkpoint blockade

Immune checkpoint blockade has demonstrated substantial promise for the treatment of several advanced malignancies. These agents activate the immune system to attack tumor cells. For example, agents targeting CTLA4 and programmed cell death 1 (PD-1) have resulted in impressive response rates and, in...

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Bibliografiske detaljer
Udgivet i:Int Immunol
Main Authors: Riaz, Nadeem, Morris, Luc, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Chan, Timothy A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986233/
https://ncbi.nlm.nih.gov/pubmed/27048318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw019
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