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NKG2D expression by CD8(+) T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT

In allogeneic hematopoietic stem cell transplantation (HSCT), controlling graft-versus-host disease (GVHD) while maintaining graft-versus-tumor (GVT) responses is of critical importance. Using a mouse model of allogeneic HSCT, we hereby demonstrate that NKG2D expression by CD8(+) T cells plays a maj...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Karimi, Mobin A., Bryson, Jerrod L., Richman, Lee P., Fesnak, Andrew D., Leichner, Theresa M., Satake, Atsushi, Vonderheide, Robert H., Raulet, David H., Reshef, Ran, Kambayashi, Taku
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458804/
https://ncbi.nlm.nih.gov/pubmed/25788701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-629006
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