High Graft CD8 Cell Dose Predicts Improved Survival and Enables Better Donor Selection in Allogeneic Stem-Cell Transplantation With Reduced-Intensity Conditioning

PURPOSE: To characterize the impact of graft T-cell composition on outcomes of reduced-intensity conditioned (RIC) allogeneic hematopoietic stem-cell transplantation (alloHSCT) in adults with hematologic malignancies. PATIENTS AND METHODS: We evaluated associations between graft T-cell doses and out...

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Publicat a:J Clin Oncol
Autors principals: Reshef, Ran, Huffman, Austin P., Gao, Amy, Luskin, Marlise R., Frey, Noelle V., Gill, Saar I., Hexner, Elizabeth O., Kambayashi, Taku, Loren, Alison W., Luger, Selina M., Mangan, James K., Nasta, Sunita D., Richman, Lee P., Sell, Mary, Stadtmauer, Edward A., Vonderheide, Robert H., Mick, Rosemarie, Porter, David L.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2015
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ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500833/
https://ncbi.nlm.nih.gov/pubmed/26056179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.60.1203
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