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Role of crosslinking for agonistic CD40 monoclonal antibodies as immune therapy of cancer

Agonists of the TNF superfamily of receptors hold promise as novel therapy for cancer. Recent data on agonistic anti-murine TNF receptors (TNFR) such as CD40 suggest that the specific engagement of Fc-receptor (FcR) is required for optimal antitumor effects, prompting calls to engineer anti-human CD...

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書誌詳細
主要な著者: Richman, Lee P., Vonderheide, Robert H.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883444/
https://ncbi.nlm.nih.gov/pubmed/24416732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0152
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