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Anti-CD40 agonist antibodies: preclinical and clinical experience

The cell-surface molecule CD40, a member of the tumor necrosis factor receptor superfamily, broadly regulates immune activation and mediates tumor apoptosis. CD40 is expressed by antigen-presenting cells (APC) and engagement of its natural ligand on T cells activates APC including dendritic cells an...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Khalil, Magi, Vonderheide, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706543/
https://ncbi.nlm.nih.gov/pubmed/19587842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.uct.2007.06.001
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