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Anti-CD40 agonist antibodies: preclinical and clinical experience
The cell-surface molecule CD40, a member of the tumor necrosis factor receptor superfamily, broadly regulates immune activation and mediates tumor apoptosis. CD40 is expressed by antigen-presenting cells (APC) and engagement of its natural ligand on T cells activates APC including dendritic cells an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706543/ https://ncbi.nlm.nih.gov/pubmed/19587842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.uct.2007.06.001 |
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