Improving the Diagnosis of Acute Hepatitis C Infection using Expanded Viral Load Criteria

Por McGovern, Barbara H., Birch, Christopher E., Bowen, Melinda J., Reyor, Laura L., Nagami, Ellen H., Chung, Raymond T., Kim, Arthur Y.
Publicado em 2009

High rates of sustained virologic response in acute hepatitis C virus infection are associated with low levels of HCV RNA and rapid virologic clearance

Por McGovern, Barbara H., Nagami, Ellen H., Birch, Christopher E., Bowen, Melinda J., Reyor, Laura L., Chung, Raymond T., Kim, Arthur Y.
Publicado em 2009

Reduced frequencies of NKp30+ NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance

Por Alter, Galit, Jost, Stephanie, Rihn, Suzannah, Reyor, Laura L, Nolan, Brian E., Ghebremichael, Musie, Bosch, Ronald, Altfeld, Marcus, Lauer, Georg M.
Publicado em 2010

Temporal dynamics of a predominant protease-inhibitor resistance mutation in a treatment naïve HCV-infected individual

Por Kim, Arthur Y., Timm, Joerg, Nolan, Brian E., Reyor, Laura L, Kane, Katherine, Berical, Andrew C., Zachary, Kimon C., Lauer, Georg M., Kuntzen, Thomas, Allen, Todd M.
Publicado em 2009

CD8 Epitope Escape and Reversion in Acute HCV Infection

Por Timm, Joerg, Lauer, Georg M., Kavanagh, Daniel G., Sheridan, Isabelle, Kim, Arthur Y., Lucas, Michaela, Pillay, Thillagavathie, Ouchi, Kei, Reyor, Laura L., zur Wiesch, Julian Schulze, Gandhi, Rajesh T., Chung, Raymond T., Bhardwaj, Nina, Klenerman, Paul, Walker, Bruce D., Allen, Todd M.
Publicado em 2004

Broadly directed virus-specific CD4(+) T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

Por Schulze zur Wiesch, Julian, Ciuffreda, Donatella, Lewis-Ximenez, Lia, Kasprowicz, Victoria, Nolan, Brian E., Streeck, Hendrik, Aneja, Jasneet, Reyor, Laura L., Allen, Todd M., Lohse, Ansgar W., McGovern, Barbara, Chung, Raymond T., Kwok, William W., Kim, Arthur Y., Lauer, Georg M.
Publicado em 2012

De Novo Generation of Escape Variant-Specific CD8(+) T-Cell Responses following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection

Por Allen, Todd M., Yu, Xu G., Kalife, Elizabeth T., Reyor, Laura L., Lichterfeld, Mathias, John, Mina, Cheng, Michael, Allgaier, Rachel L., Mui, Stanley, Frahm, Nicole, Alter, Galit, Brown, Nancy V., Johnston, Mary N., Rosenberg, Eric S., Mallal, Simon A., Brander, Christian, Walker, Bruce D., Altfeld, Marcus
Publicado em 2005

Spontaneous control of HCV is associated with the expression of HLA-B*57 and preservation of targeted epitopes

Por Kim, Arthur Y., Kuntzen, Thomas, Timm, Joerg, Nolan, Brian E., Baca, Melanie A., Reyor, Laura L., Berical, Andrew C., Feller, Andrea J., Johnson, Kristin L., Schulze Zur Wiesch, Julian, Robbins, Gregory K., Chung, Raymond T., Walker, Bruce D., Carrington, Mary, Allen, Todd M., Lauer, Georg M.
Publicado em 2010

Transmission and Long-Term Stability of Compensated CD8 Escape Mutations

Por Schneidewind, Arne, Brumme, Zabrina L., Brumme, Chanson J., Power, Karen A., Reyor, Laura L., O'Sullivan, Kristin, Gladden, Adrianne, Hempel, Ursula, Kuntzen, Thomas, Wang, Yaoyu E., Oniangue-Ndza, Cesar, Jessen, Heiko, Markowitz, Martin, Rosenberg, Eric S., Sékaly, Rafick-Pierre, Kelleher, Anthony D., Walker, Bruce D., Allen, Todd M.
Publicado em 2009

The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-...

Por Altfeld, Marcus, Allen, Todd M., Kalife, Elizabeth T., Frahm, Nicole, Addo, Marylyn M., Mothe, Bianca R., Rathod, Almas, Reyor, Laura L., Harlow, Jason, Yu, Xu G., Perkins, Beth, Robinson, Loren K., Sidney, John, Alter, Galit, Lichterfeld, Mathias, Sette, Alessandro, Rosenberg, Eric S., Goulder, Philip J. R., Brander, Christian, Walker, Bruce D.
Publicado em 2005

Compensatory Mutations Restore the Replication Defects Caused by Cytotoxic T Lymphocyte Escape Mutations in Hepatitis C Virus Polymerase

Por Oniangue-Ndza, Cesar, Kuntzen, Thomas, Kemper, Michael, Berical, Andrew, Wang, Yaoyu E., Neumann-Haefelin, Christoph, Foote, Peter Kristian, Hills-Evans, Kelsey, Reyor, Laura L., Kane, Katherine, Gladden, Adrianne D., Bloom, Allyson K., Power, Karen A., Thimme, Robert, Lauer, Georg M., Henn, Matthew R., Kim, Arthur Y., Allen, Todd M.
Publicado em 2011

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8(+) and CD4(+) T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

Por Kasprowicz, Victoria, Schulze zur Wiesch, Julian, Kuntzen, Thomas, Nolan, Brian E., Longworth, Steven, Berical, Andrew, Blum, Jenna, McMahon, Cory, Reyor, Laura L., Elias, Nahel, Kwok, William W., McGovern, Barbara G., Freeman, Gordon, Chung, Raymond T., Klenerman, Paul, Lewis-Ximenez, Lia, Walker, Bruce D., Allen, Todd M., Kim, Arthur Y., Lauer, Georg M.
Publicado em 2008

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8(+) and CD4(+) T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

Por Kasprowicz, Victoria, zur Wiesch, Julian Schulze, Kuntzen, Thomas, Nolan, Brian E., Longworth, Steven, Berical, Andrew, Blum, Jenna, McMahon, Cory, Reyor, Laura L., Elias, Nahel, Kwok, William W., McGovern, Barbara G., Freeman, Gordon, Chung, Raymond T., Klenerman, Paul, Lewis-Ximenez, Lia, Walker, Bruce D., Allen, Todd M., Kim, Arthur Y., Lauer, Georg M.
Publicado em 2011

HLA-B27 Selects for Rare Escape Mutations that Significantly Impair Hepatitis C Virus Replication and Require Compensatory Mutations

Por Neumann-Haefelin, Christoph, Oniangue-Ndza, Cesar, Kuntzen, Thomas, Schmidt, Julia, Nitschke, Katja, Sidney, John, Caillet-Saguy, Célia, Binder, Marco, Kersting, Nadine, Kemper, Michael W., Power, Karen A., Ingber, Susan, Reyor, Laura L., Hills-Evans, Kelsey, Kim, Arthur Y., Lauer, Georg M., Lohmann, Volker, Sette, Alessandro, Henn, Matthew R., Bressanelli, Stéphane, Thimme, Robert, Allen, Todd M.
Publicado em 2011

Selective Escape from CD8(+) T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Ev...

Por Allen, Todd M., Altfeld, Marcus, Geer, Shaun C., Kalife, Elizabeth T., Moore, Corey, O'Sullivan, Kristin M., DeSouza, Ivna, Feeney, Margaret E., Eldridge, Robert L., Maier, Erica L., Kaufmann, Daniel E., Lahaie, Matthew P., Reyor, Laura, Tanzi, Giancarlo, Johnston, Mary N., Brander, Christian, Draenert, Rika, Rockstroh, Jurgen K., Jessen, Heiko, Rosenberg, Eric S., Mallal, Simon A., Walker, Bruce D.
Publicado em 2005

Naturally occurring dominant resistance mutations to HCV protease and polymerase inhibitors in treatment-naïve patients

Por Kuntzen, Thomas, Timm, Joerg, Berical, Andrew, Lennon, Niall, Berlin, Aaron M., Young, Sarah K., Lee, Bongshin, Heckerman, David, Carlson, Jonathan, Reyor, Laura L., Kleyman, Marianna, McMahon, Cory M., Birch, Christopher, Wiesch, Julian Schulze zur, Ledlie, Timothy, Koehrsen, Michael, Kodira, Chinnappa, Roberts, Andrew D., Lauer, Georg M., Rosen, Hugo R., Bihl, Florian, Cerny, Andreas, Spengler, Ulrich, Liu, Zhimin, Kim, Arthur Y., Xing, Yanming, Schneidewind, Arne, Madey, Margaret A., Fleckenstein, Jaquelyn F., Park, Vicki M., Galagan, James E., Nusbaum, Chad, Walker, Bruce D., Lake-Bakaar, Gerond V., Daar, Eric S., Jacobson, Ira M., Gomperts, Edward D., Edlin, Brian R., Donfield, Sharyne M., Chung, Raymond T., Talal, Andrew H., Marion, Tony, Birren, Bruce W., Henn, Matthew R., Allen, Todd M.
Publicado em 2008