CD8 Epitope Escape and Reversion in Acute HCV Infection

In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8(+) cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70–80% of individuals develop persistent infection. Although viral escape from CD8 responses has been...

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Main Authors: Timm, Joerg, Lauer, Georg M., Kavanagh, Daniel G., Sheridan, Isabelle, Kim, Arthur Y., Lucas, Michaela, Pillay, Thillagavathie, Ouchi, Kei, Reyor, Laura L., zur Wiesch, Julian Schulze, Gandhi, Rajesh T., Chung, Raymond T., Bhardwaj, Nina, Klenerman, Paul, Walker, Bruce D., Allen, Todd M.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212005/
https://ncbi.nlm.nih.gov/pubmed/15611288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041006
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