Transmission and Long-Term Stability of Compensated CD8 Escape Mutations

Human immunodeficiency virus effectively evades CD8(+) T-cell responses through the development of CD8 escape mutations. Recent reports documenting reversion of transmitted mutations and the impact of specific escape mutations upon viral replication suggest that complex forces limit the accumulation...

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Detalhes bibliográficos
Main Authors: Schneidewind, Arne, Brumme, Zabrina L., Brumme, Chanson J., Power, Karen A., Reyor, Laura L., O'Sullivan, Kristin, Gladden, Adrianne, Hempel, Ursula, Kuntzen, Thomas, Wang, Yaoyu E., Oniangue-Ndza, Cesar, Jessen, Heiko, Markowitz, Martin, Rosenberg, Eric S., Sékaly, Rafick-Pierre, Kelleher, Anthony D., Walker, Bruce D., Allen, Todd M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663262/
https://ncbi.nlm.nih.gov/pubmed/19091871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01108-08
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