Frequent and Variable Cytotoxic-T-Lymphocyte Escape-Associated Fitness Costs in the Human Immunodeficiency Virus Type 1 Subtype B Gag Proteins

Cytotoxic-T-lymphocyte (CTL) escape mutations undermine the durability of effective human immunodeficiency virus type 1 (HIV-1)-specific CD8(+) T cell responses. The rate of CTL escape from a given response is largely governed by the net of all escape-associated viral fitness costs and benefits. The...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Boutwell, Christian L., Carlson, Jonathan M., Lin, Tien-Ho, Seese, Aaron, Power, Karen A., Peng, Jian, Tang, Yanhua, Brumme, Zabrina L., Heckerman, David, Schneidewind, Arne, Allen, Todd M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624202/
https://ncbi.nlm.nih.gov/pubmed/23365420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03233-12
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky