Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag

HIV avoids elimination by cytotoxic T-lymphocytes (CTLs) through the evolution of escape mutations. Although there is mounting evidence that these escape pathways are broadly consistent among individuals with similar human leukocyte antigen (HLA) class I alleles, previous population-based studies ha...

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Detalhes bibliográficos
Main Authors: Carlson, Jonathan M., Brumme, Zabrina L., Rousseau, Christine M., Brumme, Chanson J., Matthews, Philippa, Kadie, Carl, Mullins, James I., Walker, Bruce D., Harrigan, P. Richard, Goulder, Philip J. R., Heckerman, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579584/
https://ncbi.nlm.nih.gov/pubmed/19023406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000225
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