Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1

Por Turley, Stephen D., Valasek, Mark A., Repa, Joyce J., Dietschy, John M.
Publicado em 2010

Cyclodextrin mediates rapid changes in lipid balance in Npc1(−/−) mice without carrying cholesterol through the bloodstream

Por Taylor, Anna M., Liu, Bing, Mari, Yelenis, Liu, Benny, Repa, Joyce J.
Publicado em 2012

Carboxylesterases Are Uniquely Expressed among Tissues and Regulated by Nuclear Hormone Receptors in the Mouse

Por Jones, Ryan D., Taylor, Anna M., Tong, Ernest Y., Repa, Joyce J.
Publicado em 2013

GM2/GD2 and GM3 gangliosides have no effect on cellular cholesterol pools or turnover in normal or NPC1 mice

Por Li, Hao, Turley, Stephen D., Liu, Benny, Repa, Joyce J., Dietschy, John M.
Publicado em 2008

Inhibiting intestinal NPC1L1 activity prevents diet-induced increase in biliary cholesterol in Golden Syrian hamsters

Por Valasek, Mark A., Repa, Joyce J., Quan, Gang, Dietschy, John M., Turley, Stephen D.
Publicado em 2008

HDAC9 represses cholesterol efflux and generation of alternatively activated macrophages in atherosclerosis development

Por Cao, Qiang, Rong, Shunxing, Repa, Joyce J, Clair, Richard St., Parks, John S., Mishra, Nilamadhab
Publicado em 2014

Research Resource: Nuclear Hormone Receptor Expression in the Endocrine Pancreas

Por Chuang, Jen-Chieh, Cha, Ji-Young, Garmey, James C., Mirmira, Raghavendra G., Repa, Joyce J.
Publicado em 2008

Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(−/−) mice fed low levels of cholic acid

Por Jones, Ryan D., Repa, Joyce J., Russell, David W., Dietschy, John M., Turley, Stephen D.
Publicado em 2012

Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1(−/−) mouse

Por Liu, Benny, Turley, Stephen D., Burns, Dennis K., Miller, Anna M., Repa, Joyce J., Dietschy, John M.
Publicado em 2009

Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid

Por Liu, Benny, Ramirez, Charina M., Miller, Anna M., Repa, Joyce J., Turley, Stephen D., Dietschy, John M.
Publicado em 2010

Sustained and Selective Suppression of Intestinal Cholesterol Synthesis by Ro 48-8071, an Inhibitor of 2,3-Oxidosqualene:Lanosterol Cyclase, in the BALB/c Mouse

Por Chuang, Jen-Chieh, Valasek, Mark A., Lopez, Adam M., Posey, Kenneth S., Repa, Joyce J., Turley, Stephen D.
Publicado em 2014

Ghrelin Directly Stimulates Glucagon Secretion from Pancreatic α-Cells

Por Chuang, Jen-Chieh, Sakata, Ichiro, Kohno, Daisuke, Perello, Mario, Osborne-Lawrence, Sherri, Repa, Joyce J., Zigman, Jeffrey M.
Publicado em 2011

Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations

Por Ramirez, Charina M., Liu, Benny, Aqul, Amal, Taylor, Anna M., Repa, Joyce J., Turley, Stephen D., Dietschy, John M.
Publicado em 2011

Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice

Por Aqul, Amal, Lopez, Adam M., Posey, Kenneth S., Taylor, Anna M., Repa, Joyce J., Burns, Dennis K., Turley, Stephen D.
Publicado em 2014

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

Por Laffitte, Bryan A., Repa, Joyce J., Joseph, Sean B., Wilpitz, Damien C., Kast, Heidi R., Mangelsdorf, David J., Tontonoz, Peter
Publicado em 2001

Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP): INTERACTION OF AN α-HELIX OF ChREBP WITH THE 14-3-3 PROTEINS AND REGULATION BY PHO...

Por Sakiyama, Haruhiko, Wynn, R. Max, Lee, Wan-Ru, Fukasawa, Masashi, Mizuguchi, Hiroyuki, Gardner, Kevin H., Repa, Joyce J., Uyeda, Kosaku
Publicado em 2008

Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice

Por Jones, Ryan D., Lopez, Adam M., Tong, Ernest Y., Posey, Kenneth S., Chuang, Jen-Chieh, Repa, Joyce J., Turley, Stephen D.
Publicado no Steroids (2014)

Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs Life

Por Ramirez, Charina M., Liu, Benny, Taylor, Anna M., Repa, Joyce J., Burns, Dennis K., Weinberg, Arthur G., Turley, Stephen D., Dietschy, John M.
Publicado em 2010

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

Por Gustavsson, Natalia, Lao, Ye, Maximov, Anton, Chuang, Jen-Chieh, Kostromina, Elena, Repa, Joyce J., Li, Cai, Radda, George K., Südhof, Thomas C., Han, Weiping
Publicado em 2008

Role of Calcium and EPAC in Norepinephrine-Induced Ghrelin Secretion

Por Mani, Bharath K., Chuang, Jen-Chieh, Kjalarsdottir, Lilja, Sakata, Ichiro, Walker, Angela K., Kuperman, Anna, Osborne-Lawrence, Sherri, Repa, Joyce J., Zigman, Jeffrey M.
Publicado em 2014