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Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1

Cholesterol homeostasis in the enterocyte is regulated by the interplay of multiple genes that ultimately determines the net amount of cholesterol reaching the circulation from the small intestine. The effect of deleting these genes, particularly acyl CoA:cholesterol acyl transferase 2 (ACAT2), on c...

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Detalhes bibliográficos
Main Authors: Turley, Stephen D., Valasek, Mark A., Repa, Joyce J., Dietschy, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993165/
https://ncbi.nlm.nih.gov/pubmed/20724527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00190.2010
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