Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLs

Intestinal cholesterol absorption involves the chylomicron and HDL pathways and is dependent on microsomal triglyceride transfer protein (MTP) and ABCA1, respectively. Chylomicrons transport free and esterified cholesterol, whereas HDLs transport free cholesterol. ACAT2 esterifies cholesterol for se...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Iqbal, Jahangir, Boutjdir, Mohamed, Rudel, Lawrence L., Hussain, M. Mahmood
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617129/
https://ncbi.nlm.nih.gov/pubmed/25030663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047951
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