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IRE1β Inhibits Chylomicron Production by Selectively Degrading MTP mRNA
Microsomal triglyceride transfer protein (MTP) is needed to assemble chylomicrons in the endoplasmic reticulum (ER) of enterocytes. We explored the role of an ER stress protein, inositol-requiring enzyme 1β (IRE1β), in regulating this process. High-cholesterol and high-fat diets decreased intestinal...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435513/ https://ncbi.nlm.nih.gov/pubmed/18460335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.03.005 |
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