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IRE1β Inhibits Chylomicron Production by Selectively Degrading MTP mRNA
Microsomal triglyceride transfer protein (MTP) is needed to assemble chylomicrons in the endoplasmic reticulum (ER) of enterocytes. We explored the role of an ER stress protein, inositol-requiring enzyme 1β (IRE1β), in regulating this process. High-cholesterol and high-fat diets decreased intestinal...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435513/ https://ncbi.nlm.nih.gov/pubmed/18460335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.03.005 |
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