IRE1β Inhibits Chylomicron Production by Selectively Degrading MTP mRNA

Microsomal triglyceride transfer protein (MTP) is needed to assemble chylomicrons in the endoplasmic reticulum (ER) of enterocytes. We explored the role of an ER stress protein, inositol-requiring enzyme 1β (IRE1β), in regulating this process. High-cholesterol and high-fat diets decreased intestinal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Iqbal, Jahangir, Dai, Kezhi, Seimon, Tracie, Jungreis, Rivka, Oyadomari, Miho, Kuriakose, George, Ron, David, Tabas, Ira, Hussain, M. Mahmood
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435513/
https://ncbi.nlm.nih.gov/pubmed/18460335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.03.005
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