Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation

The hypothesis tested in this study was that cholesterol esterification by ACAT2 would increase cholesterol absorption efficiency by providing cholesteryl ester (CE) for incorporation into chylomicrons. The assumption was that absorption would be proportional to Acat2 gene dosage. Male ACAT2(+/+), A...

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Bibliographic Details
Main Authors: Nguyen, Tam M., Sawyer, Janet K., Kelley, Kathryn L., Davis, Matthew A., Rudel, Lawrence L.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2012
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243485/
https://ncbi.nlm.nih.gov/pubmed/22045928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M018820
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