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Intestine-specific MTP and global ACAT2 deficiency lowers acute cholesterol absorption with chylomicrons and HDLs

Intestinal cholesterol absorption involves the chylomicron and HDL pathways and is dependent on microsomal triglyceride transfer protein (MTP) and ABCA1, respectively. Chylomicrons transport free and esterified cholesterol, whereas HDLs transport free cholesterol. ACAT2 esterifies cholesterol for se...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Main Authors: Iqbal, Jahangir, Boutjdir, Mohamed, Rudel, Lawrence L., Hussain, M. Mahmood
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617129/
https://ncbi.nlm.nih.gov/pubmed/25030663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047951
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