Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice

Because apoB-containing lipoproteins are pro-atherogenic and their secretion by liver and intestine largely depends on microsomal triglyceride transfer protein (MTP) activity, MTP inhibition strategies are actively pursued. How decreasing the secretion of apoB-containing lipoproteins affects intrace...

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Bibliografiske detaljer
Main Authors: Dikkers, Arne, Annema, Wijtske, de Boer, Jan Freark, Iqbal, Jahangir, Hussain, M. Mahmood, Tietge, Uwe J. F.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995460/
https://ncbi.nlm.nih.gov/pubmed/24511105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M042986
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