ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma

ApoE plays an important role in lipoprotein metabolism. This study investigated the effects of adenovirus-mediated human apoE overexpression (AdhApoE3) on sterol metabolism and in vivo reverse cholesterol transport (RCT). In wild-type mice, AdhApoE3 resulted in decreased HDL cholesterol levels and a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Annema, Wijtske, Dikkers, Arne, Freark de Boer, Jan, Gautier, Thomas, Rensen, Patrick C. N., Rader, Daniel J., Tietge, Uwe J. F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329392/
https://ncbi.nlm.nih.gov/pubmed/22383685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M020743
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados