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Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1

Cholesterol homeostasis in the enterocyte is regulated by the interplay of multiple genes that ultimately determines the net amount of cholesterol reaching the circulation from the small intestine. The effect of deleting these genes, particularly acyl CoA:cholesterol acyl transferase 2 (ACAT2), on c...

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Bibliografski detalji
Glavni autori: Turley, Stephen D., Valasek, Mark A., Repa, Joyce J., Dietschy, John M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993165/
https://ncbi.nlm.nih.gov/pubmed/20724527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00190.2010
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