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Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

Vertebrates express at least 15 different synaptotagmins with the same domain structure but diverse localizations and tissue distributions. Synaptotagmin-1,-2, and -9 act as calcium sensors for the fast phrase of neurotransmitter release, and synaptotagmin-12 acts as a calcium-independent modulator...

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Autors principals: Gustavsson, Natalia, Lao, Ye, Maximov, Anton, Chuang, Jen-Chieh, Kostromina, Elena, Repa, Joyce J., Li, Cai, Radda, George K., Südhof, Thomas C., Han, Weiping
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268794/
https://ncbi.nlm.nih.gov/pubmed/18308938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711700105
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