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Synaptotagmin-7 is a principal Ca(2+) sensor for Ca(2+)-induced glucagon exocytosis in pancreas
Hormones such as glucagon are secreted by Ca(2+)-induced exocytosis of large dense-core vesicles, but the mechanisms involved have only been partially elucidated. Studies of pancreatic β-cells secreting insulin revealed that synaptotagmin-7 alone is not sufficient to mediate Ca(2+)-dependent insulin...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674989/ https://ncbi.nlm.nih.gov/pubmed/19171650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.168005 |
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