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Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities

Synaptotagmins constitute a large family of membrane proteins implicated in Ca(2+)-triggered exocytosis. Structurally similar synaptotagmins are differentially localized either to secretory vesicles or to plasma membranes, suggesting distinct functions. Using measurements of the Ca(2+) affinities of...

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Detalhes bibliográficos
Main Authors: Sugita, Shuzo, Shin, Ok-Ho, Han, Weiping, Lao, Ye, Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125835/
https://ncbi.nlm.nih.gov/pubmed/11823420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.3.270
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