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Synaptotagmin-1 and -7 are functionally overlapping Ca(2+) sensors for exocytosis in adrenal chromaffin cells

Synaptotagmin-1, the canonical isoform of the synaptotagmin family, is a Ca(2+) sensor for fast synchronous neurotransmitter release in forebrain neurons and chromaffin cells. Even though deletion of synaptotagmin-1 abolishes fast exocytosis in chromaffin cells, it reduces overall secretion by only...

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Detalhes bibliográficos
Main Authors: Schonn, Jean-Sébastien, Maximov, Anton, Lao, Ye, Südhof, Thomas C., Sørensen, Jakob B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268838/
https://ncbi.nlm.nih.gov/pubmed/18308932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712373105
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