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Examining Synaptotagmin 1 Function in Dense Core Vesicle Exocytosis under Direct Control of Ca(2+)
We tested the long-standing hypothesis that synaptotagmin 1 is the Ca(2+) sensor for fast neurosecretion by analyzing the intracellular Ca(2+) dependence of large dense-core vesicle exocytosis in a mouse strain carrying a mutated synaptotagmin C2A domain. The mutation (R233Q) causes a twofold increa...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2003
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234490/ https://ncbi.nlm.nih.gov/pubmed/12939392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308855 |
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