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Unexpected Ca(2+)-binding properties of synaptotagmin 9

Synaptotagmin 1 (Syt 1) functions as an essential Ca(2+) sensor for the fast but not slow component of Ca(2+)-triggered exocytosis. One hypothesis to account for this selective function, based on the close homology of Syt 1 with synaptotagmin 9 (Syt 9), is that these Syts are redundant for the slow...

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Autors principals: Shin, Ok-Ho, Maximov, Anton, Lim, Byung Kook, Rizo, Josep, Südhof, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC356988/
https://ncbi.nlm.nih.gov/pubmed/14983047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308477100
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