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Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release

Central synapses exhibit spontaneous neurotransmitter release that is selectively regulated by cAMP-dependent protein kinase A (PKA). We now show that synaptic vesicles contain synaptotagmin-12, a synaptotagmin isoform that differs from classical synaptotagmins in that it does not bind Ca(2+). In sy...

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Detalhes bibliográficos
Main Authors: Maximov, Anton, Shin, Ok-Ho, Liu, Xinran, Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063632/
https://ncbi.nlm.nih.gov/pubmed/17190793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607021
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