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Genetic analysis of synaptotagmin 2 in spontaneous and Ca(2+)-triggered neurotransmitter release
Synaptotagmin 2 resembles synaptotagmin 1, the Ca(2+) sensor for fast neurotransmitter release in forebrain synapses, but little is known about synaptotagmin 2 function. Here, we describe a severely ataxic mouse strain that harbors a single, destabilizing amino-acid substitution (I377N) in synaptota...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462977/ https://ncbi.nlm.nih.gov/pubmed/16642042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601103 |
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