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A Quaternary SNARE-Synaptotagmin-Ca(2+)-Phospholipid Complex in Neurotransmitter Release

The function of synaptotagmin as a Ca(2+) sensor in neurotransmitter release involves Ca(2+)-dependent phospholipid binding to its two C(2) domains, but this activity alone does not explain why Ca(2+) binding to the C(2)B domain is more critical for release than Ca(2+) binding to the C(2)A domain. S...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dai, Han, Shen, Nan, Araç, Demet, Rizo, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855161/
https://ncbi.nlm.nih.gov/pubmed/17320903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.01.040
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