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Subtle Interplay between Synaptotagmin- and Complexin-Binding to the SNARE complex

Ca(2+)-triggered neurotransmitter release depends on the formation of SNARE complexes that bring the synaptic vesicle and plasma membranes together, on the Ca(2+) sensor synaptotagmin-1, and on complexins, which play active and inhibitory roles. Release of the complexin inhibitory activity by bindin...

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Autors principals: Xu, Junjie, Brewer, Kyle D., Perez-Castillejos, Raquel, Rizo, Josep
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786701/
https://ncbi.nlm.nih.gov/pubmed/23845424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.07.001
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