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Augmenting neurotransmitter release by enhancing the apparent Ca(2+) affinity of synaptotagmin 1
Synaptotagmin 1 likely acts as a Ca(2+) sensor in neurotransmitter release by Ca(2+)-binding to its two C2 domains. This notion was strongly supported by the observation that a mutation in the C2A domain causes parallel decreases in the apparent Ca(2+) affinity of synaptotagmin 1 and in the Ca(2+) s...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1311909/ https://ncbi.nlm.nih.gov/pubmed/16352718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509153102 |
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