LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

Apolipoprotein E (apoE) secreted by macrophages in the artery wall exerts an important protective effect against the development of atherosclerosis, presumably through its ability to promote lipid efflux. Previous studies have shown that increases in cellular free cholesterol levels stimulate apoE t...

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Main Authors: Laffitte, Bryan A., Repa, Joyce J., Joseph, Sean B., Wilpitz, Damien C., Kast, Heidi R., Mangelsdorf, David J., Tontonoz, Peter
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC14617/
https://ncbi.nlm.nih.gov/pubmed/11149950
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