Role of LXRs in control of lipogenesis

The discovery of oxysterols as the endogenous liver X receptor (LXR) ligands and subsequent gene targeting studies in mice provided strong evidence that LXR plays a central role in cholesterol metabolism. The identification here of a synthetic, nonsteroidal LXR-selective agonist series represented b...

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Detalhes bibliográficos
Main Authors: Schultz, Joshua R., Tu, Hua, Luk, Alvin, Repa, Joyce J., Medina, Julio C., Li, Leping, Schwendner, Susan, Wang, Shelley, Thoolen, Martin, Mangelsdorf, David J., Lustig, Kevin D., Shan, Bei
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC317060/
https://ncbi.nlm.nih.gov/pubmed/11090131
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