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Linking lipids, Alzheimer's and LXRs?

Deposition of the β-amyloid (Aβ) peptide is thought to underlie development of Alzheimer's disease (AD). This pathological linkage has spurred considerable interest in therapeutic strategies to reduce Aβ production. It is becoming increasingly clear that altered cholesterol homeostasis can modu...

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Detalhes bibliográficos
Main Authors: Patel, Nilay V., Forman, Barry Marc
Formato: Artigo
Idioma:Inglês
Publicado em: The Nuclear Receptor Signaling Atlas 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1402230/
https://ncbi.nlm.nih.gov/pubmed/16604185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.02001
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