Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

LXRα is a nuclear receptor that has previously been shown to regulate the metabolic conversion of cholesterol to bile acids. Here we define a role for this transcription factor in the control of cellular cholesterol efflux. We demonstrate that retroviral expression of LXRα in NIH 3T3 fibroblasts or...

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Bibliographic Details
Main Authors: Venkateswaran, Asha, Laffitte, Bryan A., Joseph, Sean B., Mak, Puiying A., Wilpitz, Damien C., Edwards, Peter A., Tontonoz, Peter
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17300/
https://ncbi.nlm.nih.gov/pubmed/11035776
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