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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

LXRα is a nuclear receptor that has previously been shown to regulate the metabolic conversion of cholesterol to bile acids. Here we define a role for this transcription factor in the control of cellular cholesterol efflux. We demonstrate that retroviral expression of LXRα in NIH 3T3 fibroblasts or...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Venkateswaran, Asha, Laffitte, Bryan A., Joseph, Sean B., Mak, Puiying A., Wilpitz, Damien C., Edwards, Peter A., Tontonoz, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11035776/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.200367697
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