High Throughput Substrate Phage Display for Protease Profiling

Por Ratnikov, Boris, Cieplak, Piotr, Smith, Jeffrey W.
Publicado em 2009

Right on TARGET: glutamine metabolism in cancer

Por Ratnikov, Boris, Jeon, Young Joo, Smith, Jeffrey W., Ronai, Ze'ev A.
Publicado no Oncoscience (2015)

CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events

Por Kumar, Sonu, Ratnikov, Boris I., Kazanov, Marat D., Smith, Jeffrey W., Cieplak, Piotr
Publicado no PLoS One (2015)

Correction: CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events

Por Kumar, Sonu, Ratnikov, Boris I., Kazanov, Marat D., Smith, Jeffrey W., Cieplak, Piotr
Publicado no PLoS One (2015)

Virtual Ligand Screening of the National Cancer Institute (NCI) Compound Library Leads to the Allosteric Inhibitory Scaffolds of the West Nile Virus NS3 Proteinase

Por Shiryaev, Sergey A., Cheltsov, Anton V., Gawlik, Katarzyna, Ratnikov, Boris I., Strongin, Alex Y.
Publicado em 2011

Metabolic rewiring in melanoma

Por Ratnikov, Boris I., Scott, David A., Osterman, Andrei L., Smith, Jeffrey W., Ronai, Ze’ev A.
Publicado no Oncogene (2016)

Cleavage preference distinguishes the two-component NS2B–NS3 serine proteinases of Dengue and West Nile viruses

Por Shiryaev, Sergey A., Kozlov, Igor A., Ratnikov, Boris I., Smith, Jeffrey W., Lebl, Michal, Strongin, Alex Y.
Publicado em 2007

Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma

Por Filipp, Fabian V., Ratnikov, Boris, De Ingeniis, Jessica, Smith, Jeffrey W., Osterman, Andrei L., Scott, David A.
Publicado em 2012

Expression and purification of a two-component flaviviral proteinase resistant to autocleavage at the NS2B-NS3 junction region

Por Shiryaev, Sergey A., Aleshin, Alexander E., Ratnikov, Boris I., Smith, Jeffrey W., Liddington, Robert C., Strongin, Alex Y.
Publicado em 2006

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma

Por Ratnikov, Boris, Aza-Blanc, Pedro, Ronai, Ze'ev A., Smith, Jeffrey W., Osterman, Andrei L., Scott, David A.
Publicado no Oncotarget (2015)

Matrix Metalloproteinase Proteolysis of the Myelin Basic Protein Isoforms Is a Source of Immunogenic Peptides in Autoimmune Multiple Sclerosis

Por Shiryaev, Sergey A., Savinov, Alexei Y., Cieplak, Piotr, Ratnikov, Boris I., Motamedchaboki, Khatereh, Smith, Jeffrey W., Strongin, Alex Y.
Publicado em 2009

Structure-activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase

Por Sidique, Shyama, Shiryaev, Sergey A., Ratnikov, Boris I., Herath, Ananda, Su, Ying, Strongin, Alex Y., Cosford, Nicholas D. P.
Publicado em 2009

The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase

Por Chernov, Andrei V., Shiryaev, Sergey A., Aleshin, Alexander E., Ratnikov, Boris I., Smith, Jeffrey W., Liddington, Robert C., Strongin, Alex Y.
Publicado em 2008

Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B–NS3 proteinase of West Nile virus

Por SHIRYAEV, Sergey A., RADICHEV, Ilian A., RATNIKOV, Boris I., ALESHIN, Alexander E., GAWLIK, Katarzyna, STEC, Boguslaw, FRISCH, Christian, KNAPPIK, Achim, STRONGIN, Alex Y.
Publicado em 2010

Recreation of the terminal events in physiological integrin activation

Por Ye, Feng, Hu, Guiqing, Taylor, Dianne, Ratnikov, Boris, Bobkov, Andrey A., McLean, Mark A., Sligar, Stephen G., Taylor, Kenneth A., Ginsberg, Mark H.
Publicado em 2010

Structural determinants of limited proteolysis

Por Kazanov, Marat D., Igarashi, Yoshinobu, Eroshkin, Alexey M., Cieplak, Piotr, Ratnikov, Boris, Zhang, Ying, Li, Zhanwen, Godzik, Adam, Osterman, Andrei L., Smith1, Jeffrey W.
Publicado em 2011

Switching the Substrate Specificity of the Two-Component NS2B-NS3 Flavivirus Proteinase by Structure-Based Mutagenesis

Por Shiryaev, Sergey A., Ratnikov, Boris I., Aleshin, Alexander E., Kozlov, Igor A., Nelson, Nicholas A., Lebl, Michal, Smith, Jeffrey W., Liddington, Robert C., Strongin, Alex Y.
Publicado em 2007

Basis for substrate recognition and distinction by matrix metalloproteinases

Por Ratnikov, Boris I., Cieplak, Piotr, Gramatikoff, Kosi, Pierce, James, Eroshkin, Alexey, Igarashi, Yoshinobu, Kazanov, Marat, Sun, Qing, Godzik, Adam, Osterman, Andrei, Stec, Boguslaw, Strongin, Alex, Smith, Jeffrey W.
Publicado em 2014

Functional Specialization in Proline Biosynthesis of Melanoma

Por De Ingeniis, Jessica, Ratnikov, Boris, Richardson, Adam D., Scott, David A., Aza-Blanc, Pedro, De, Surya K., Kazanov, Marat, Pellecchia, Maurizio, Ronai, Ze'ev, Osterman, Andrei L., Smith, Jeffrey W.
Publicado em 2012

Internal Cleavages of the Autoinhibitory Prodomain Are Required for Membrane Type 1 Matrix Metalloproteinase Activation, although Furin Cleavage Alone Generates Inactive Proteinase

Por Golubkov, Vladislav S., Cieplak, Piotr, Chekanov, Alexei V., Ratnikov, Boris I., Aleshin, Alexander E., Golubkova, Natalya V., Postnova, Tatiana I., Radichev, Ilian A., Rozanov, Dmitri V., Zhu, Wenhong, Motamedchaboki, Khatereh, Strongin, Alex Y.
Publicado em 2010