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Cleavage preference distinguishes the two-component NS2B–NS3 serine proteinases of Dengue and West Nile viruses
Regulated proteolysis of the polyprotein precursor by the NS2B–NS3 protease is required for the propagation of infectious virions. Unless the structural and functional parameters of NS2B–NS3 are precisely determined, an understanding of its functional role and the design of flaviviral inhibitors wil...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1770841/ https://ncbi.nlm.nih.gov/pubmed/17067286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061136 |
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