The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase

Similar to many flavivirus types including Dengue and yellow fever viruses, the nonstructural NS3 multifunctional protein of West Nile virus (WNV) with an N-terminal serine proteinase domain and an RNA triphosphatase, an NTPase domain, and an RNA helicase in the C-terminal domain is implicated in bo...

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Detalhes bibliográficos
Main Authors: Chernov, Andrei V., Shiryaev, Sergey A., Aleshin, Alexander E., Ratnikov, Boris I., Smith, Jeffrey W., Liddington, Robert C., Strongin, Alex Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Transcription, Chromatin, and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427327/
https://ncbi.nlm.nih.gov/pubmed/18442976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801719200
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