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Recreation of the terminal events in physiological integrin activation

Increased affinity of integrins for the extracellular matrix (activation) regulates cell adhesion and migration, extracellular matrix assembly, and mechanotransduction. Major uncertainties concern the sufficiency of talin for activation, whether conformational change without clustering leads to acti...

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Detalhes bibliográficos
Main Authors: Ye, Feng, Hu, Guiqing, Taylor, Dianne, Ratnikov, Boris, Bobkov, Andrey A., McLean, Mark A., Sligar, Stephen G., Taylor, Kenneth A., Ginsberg, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812850/
https://ncbi.nlm.nih.gov/pubmed/20048261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908045
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