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PIP2 Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates its Auto-Inhibited Form
Integrins are vital transmembrane receptors that mediate cell-cell and cell extra-cellular matrix (ECM) interactions and signaling. Talin is a 270 kDa protein and is considered a key regulator of integrin activity. The interaction between talin and integrin is commonly regarded as the final step of...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808563/ https://ncbi.nlm.nih.gov/pubmed/27548281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00497 |
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