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Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers

One of the biggest challenges in pharmaceutical research is obtaining integral membrane proteins in a functional, solubilized, and monodisperse state that provides a native-like environment that maintains the spectrum of in vivo activities. Many of these integral membrane proteins are receptors, enz...

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Detalhes bibliográficos
Main Authors: Bayburt, Timothy H., Sligar, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366955/
https://ncbi.nlm.nih.gov/pubmed/14573860
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