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Modulation of the Cytochrome P450 Reductase Redox Potential by the Phospholipid Bilayer

Cytochrome P450 reductase (CPR) is a tethered membrane protein which transfers electrons from NADPH to microsomal P450s. We show that the lipid bilayer has a role in defining the redox potential of the CPR flavin domains. In order to quantitate the electrochemical behavior of this central redox prot...

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Detalhes bibliográficos
Main Authors: Das, Aditi, Sligar, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797566/
https://ncbi.nlm.nih.gov/pubmed/19908820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9011435
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