Carboxylesterase inhibitors

door Hatfield, M. Jason, Potter, Philip M.
Gepubliceerd in 2011

The development and application of small molecule modulators of SF3b as therapeutic agents for cancer

door Webb, Thomas R., Joyner, Amanda S., Potter, Philip M.
Gepubliceerd in 2012

Tumour‐selective targeting of drug metabolizing enzymes to treat metastatic cancer

door Wierdl, Monika, Tsurkan, Lyudmila, Hatfield, M Jason, Potter, Philip M
Gepubliceerd in Br J Pharmacol (2016)

Modifications of human carboxylesterase for improved prodrug activation

door Hatfield, M. Jason, Wierdl, Monika, Wadkins, Randy M., Potter, Philip M.
Gepubliceerd in 2008

Hydrolysis of Pyrethroids by Human and Rat Tissues: Examination of Intestinal, Liver and Serum Carboxylesterases

door Crow, J. Allen, Borazjani, Abdolsamad, Potter, Philip M., Ross, Matthew K.
Gepubliceerd in 2007

In Silico Design and Evaluation of Carboxylesterase Inhibitors

door Stoddard, Shana V., Yu, Xiaozhen, Potter, Philip M., Wadkins, Randy M.
Gepubliceerd in 2010

Control of RhoA Methylation by Carboxylesterase I

door Cushman, Ian, Cushman, Stephanie M., Potter, Philip M., Casey, Patrick J.
Gepubliceerd in 2013

Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors

door Binder, Randall J., Hatfield, M. Jason, Chi, Liying, Potter, Philip M.
Gepubliceerd in Eur J Med Chem (2018)

Challenges and Opportunities with Non-CYP Enzymes Aldehyde oxidase, Carboxylesterase and UDP-glucuronosyl transferase: Focus on Reaction Phenotyping and Prediction of Human Clearan...

door Argikar, Upendra A., Potter, Philip M., Hutzler, J. Matthew, Marathe, Punit H.
Gepubliceerd in AAPS J (2016)

Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure–activity relationship analysis

door Harada, Toshiyuki, Nakagawa, Yoshiaki, Wadkins, Randy M., Potter, Philip M., Wheelock, Craig E.
Gepubliceerd in 2008

Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing

door Fan, Liying, Lagisetti, Chandraiah, Edwards, Carol C., Webb, Thomas R., Potter, Philip M.
Gepubliceerd in 2011

Covalent Inhibition of Recombinant Human Carboxylesterase 1 and 2 and Monoacylglycerol Lipase by the Carbamates JZL184 and URB597

door Crow, J. Allen, Bittles, Victoria, Borazjani, Abdolsamad, Potter, Philip M., Ross, Matthew K.
Gepubliceerd in 2012

Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors

door Tsurkan, Lyudmila G., Hatfield, M. Jason, Edwards, Carol C., Hyatt, Janice L., Potter, Philip M.
Gepubliceerd in 2012

Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids

door Crow, J. Allen, Herring, Katye L., Xie, Shuqi, Borazjani, Abdolsamad, Potter, Philip M., Ross, Matthew K.
Gepubliceerd in 2009

Inhibition of Recombinant Human Carboxylesterase 1 and 2 and Monoacylglycerol Lipase by Chlorpyrifos Oxon, Paraoxon and Methyl Paraoxon

door Crow, J. Allen, Bittles, Victoria, Herring, Katye L., Borazjani, Abdolsamad, Potter, Philip M., Ross, Matthew K.
Gepubliceerd in 2011

Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: Role of carboxylesterase 1 and 2

door Xie, Shuqi, Borazjani, Abdolsamad, Hatfield, M. Jason, Edwards, Carol C., Potter, Philip M., Ross, Matthew K.
Gepubliceerd in 2010

Potent, irreversible inhibition of human carboxylesterases by tanshinone anhydrides isolated from Salvia miltiorrhiza (“Danshen”)

door Hatfield, M. Jason, Binder, Randall J., Gannon, Rowan, Fratt, Ellie M., Bowling, John, Potter, Philip M.
Gepubliceerd in J Nat Prod (2018)

Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages

door Crow, J. Allen, Middleton, Brandy L., Borazjani, Abdolsamad, Hatfield, M. Jason, Potter, Philip M., Ross, Matthew K.
Gepubliceerd in 2008

Nanoparticles Containing Anti-inflammatory Agents as Chemotherapy Adjuvants II: Role of Plasma Esterases in Drug Release

door Lu, Xiuling, Howard, Melissa D., Talbert, Dominique R., Rinehart, John J., Potter, Philip M., Jay, Michael, Leggas, Markos
Gepubliceerd in 2009

Global and local molecular dynamics of a bacterial carboxylesterase provide insight into its catalytic mechanism

door Yu, Xiaozhen, Sigler, Sara C., Hossain, Delwar, Wierdl, Monika, Gwaltney, Steven R., Potter, Philip M., Wadkins, Randy M.
Gepubliceerd in 2011